I can disprove some theories others have posted here. I have tried the following without getting La Comodora's variant to unlock.
1) In "Time Cataclysm", La Comodora had a copy of every equipment card in play, used every equipment card, did not use her "destroy equipment card at start of turn" ability until the final turn, played "Run Aground" to deal massive damage that incapacitated the villain. Note that she did *not* have ""Concordant Helm" in her trash.
2) In "Time Cataclysm", La Comodora has a copy of every equipment card in her trash, did not use her "destroy equipment card at start of turn" ability until the final turn, played "Run Aground" to deal massive damage that incapacitated the villain.
When I have time, I'll try the combination of these (a copy of every equipment card in play, a copy of every equipment card used, a copy of every equipment card in the trash).
I have tried SO MANY variations trying for this unlock. On the plus side, I have learned a lot about how La Comodora works. On the minus side, I have spent so much time on this...
UPDATE:
GOT THE VARIANT UNLOCK with the combination of the two attempts listed above.
This is what I did:
In "Time Cataclysm":
- La Comodora had a copy of every equipment card in play;
- used every equipment card;
- had a copy of every equipment card in the trash (even *before* the final turn when at the start of her turn she destroyed every equipment card in play and then played "Run Aground");
- did not use her "destroy equipment card at start of turn" ability until the final turn and then played "Run Aground" to deal massive damage that incapacitated the villain.
La Comodora played no ongoing cards and I don't think she played any one-shots until the final "Run Aground".
Some of these steps might be extraneous, but I believe I have proved that a copy of every equipment card must be in La Comodora's trash pile. Also, am pretty sure the "no destroying equipment cards in play until the final turn" is a requirement from (many) previous games.
Now onto this week's one-shot and then "Completionist Guise", my final variant to unlock.