Ambuscade, Baron Balde, La Capitan, and Greazer, Advanced, against Setback, the Scholar of the Infinite, the Argent Adept, and Nightmist in the Tomb of Anubis.
Got this Fine on my third attempt. Some thoughts (cross posted from Steam):
Impulsion Beam is probably my least favorite card in the game, especially with Advanced Vengeance Baron Blade. Cards that let cards come out but that don't count as being played or that play cards out of turn sequence are key. (You'll get some of those up front, thankfully.)
There's going to be a fair bit of redirection. Make some of it work for you.
If you can keep Flesh to Iron alive, the Scholar is an absolute tank.
The Argent Adept is not going to last long. Get whatever use out of him you can and then let him flip. His incap will at least let you get more powers going and maybe even more cards out, with Setback's base power.
Trials hit Villain cards too. Let them.